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第12年
- 入驻时间： 2012-04-17
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- 电话：400-968-7988
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- Email：fuwu@bioleaf.com
产品详情
简单介绍：
CD20 Antibody (FITC)
详情介绍：
CD20 is present on all normal B cells in peripheral blood, lymph nodes, spleen, tonsil and bone marrow. The antigen is also present on most B cell lines and on non-T ALL and CLL cells.
| Target | CD20 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Tested Applications | FCM |
| Recommended dilutions | FCM: 20 μl/1 million cells. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen | Normal human lymphocytes from lymph node. |
| Purification | Affinity Chromatography |
| Form | Liquid |
| Isotype | IgG2a |
| Conjugation | FITC |
| Specificity | CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82. |
| Storage | Store in the dark at 2-8 °C. |
| Molecular Weight | 37/35 kDa |
| Swiss Prot | P11836 |
| GeneID | 931 |
| Buffer | The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide |
| Availability | Shipped within 3-5 working days. |
| Note | This product is for research use only. |
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