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第12年
- 入驻时间： 2012-04-17
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- 电话：400-968-7988
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- Email：fuwu@bioleaf.com
产品详情
简单介绍：
CSNK2A1 Human
详情介绍：
Catalogue number
PKA-208
Synonyms
Casein kinase II subunit alpha, EC 2.7.11.1, CK II, CK2A1, CKII alpha, CSNK2A1, PKCK2, CSK21.
Introduction
The Casein kinase 2 (EC2.7.11.1) is a serine/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase 2.
Mice that lack casein kinase 2 alpha prime have a defect in the morphology of developing sperm.
Mice that lack casein kinase 2 alpha prime have a defect in the morphology of developing sperm.
Description
Casein Kinase 2 alpha 1 Human Recombinant is a non-glycosylated polypeptide having a molecular mass of 45.1 kDa.
Casein Kinase 2 is purified by proprietary chromatographic techniques.
Casein Kinase 2 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
CSNK2A1 is supplied in 25mM Tris-HCl, 500mM NaCl, 1mM DTT, 500μm PMSF, 50% glycerol, pH 8.5.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Avoid multiple freeze-thaw cycles.
Unit Definition
No protease activity detectable, specific activity > 1.320 U/mg
(1U = 1µmol/min at 37 degree C) using the synthetic peptide RRRDDDSDDD.
(1U = 1µmol/min at 37 degree C) using the synthetic peptide RRRDDDSDDD.
Purity
Greater than 99% as determined by SDS-PAGE.
Safety Data Sheet
SDS
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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