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产品介绍 |
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品名 |
Quidel Polyclonal Antiserum to Human C1 Inhibitor (C1 Esterase) |
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货号 |
A300 |
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规格 |
2.0 mL |
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形式 |
Whole Antiserum |
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防腐剂 |
≤ 0.1% Sodium Azide |
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物种交叉反应 |
Baboon, Dog, Rabbit |
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储存 |
2°C to 8°C (≤ 30 days) For long-term storage (> 30 days), aliquot and store at ≤ –20°C. Avoid repeated freeze-thaw. |
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使用说明 |
For Research Use Only. Not for use in diagnostic procedures |
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产品描述 |
Highly purified human C1-inhibitor was isolated from normal serum and used to immunize goats. The C1-inhibitor polyclonal antisera was tested against normal human plasma by double immunodiffusion, one-dimensional immunoelectrophoresis, quantitative radial immunodiffusion, and quantitative rocket immunoelectrophoresis. The antiserum was determined to be monospecific for C1-inhibitor at varying concentrations.
Quidel Polyclonal Antiserum to Human C1 Inhibitor (C1 Esterase) |
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背景 |
C1-inhibitor is a multispecific protease inhibitor present in human plasma and serum. Normal human serum shows a concentration of approximately 200 µg/mL. C1-inhibitor is a glycoprotein with an approximate molecular weight of 110 kD. This protein contains many glycosylation sites, so the molecular weight varies depending on the quantity of sites that are glycosylated
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应用 |
Applications of the C1-inhibitor polyclonal antisera have been evaluated by various research facilities, and include Western Blot 1 and Immunoblot. 2 |
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参考文献 |
Schwab, J. et al. “Borrelia valaisiana Resist Complement-Mediated Killing Independently of the Recruitment of Immune Regulators and Inactivation of Complement Components.” PLoS ONE 8(1): e53659. Yasojima, K., et al. “Complement Components, but Not Complement Inhibitors, are Upregulated in Atherosclerotic Plaques.” Arteriosclerosis, Thrombosis, and Vascular Biology (2001): 1214-1219
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