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第12年
- 入驻时间: 2012-04-17
- 联系人:客户经理
- 电话:400-968-7988
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- Email:fuwu@bioleaf.com
产品详情
简单介绍:
CD33 Antibody
详情介绍:
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2, 6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Target | CD33 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Tested Applications | IF/ICC |
Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
Immunogen | Human CD33. |
Purification | Purified Mouse Monoclonal Antibody. |
Isotype | IgM |
Conjugation | Unconjugated |
Specificity | This CD33 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 337-364 amino acids from human CD33. |
Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
Swiss Prot | P20138 |
Buffer | PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |
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