世联博研(北京)科技有限公司
扫一扫,手机逛起来
主营:Flexcell细胞力学和regenhu细胞3D生物打印机销售技术服务: 美国Flexcell品牌FX-5000T细胞牵张应力加载培养系统,FX-5K细胞显微牵张应力加载培养系统,Tissue Train三维细胞组织培养与测试系统,FX-5000C三维细胞组织压应力加载培养系统,STR-4000细胞流体剪切应力加载培养系统,德国cellastix品牌Optical Stretcher高通量单细胞牵引应变与分析系统 Regenhu品牌3D discovery细胞友好型3D生物打印机,piuma细胞纳米压痕测试分析、aresis多点力学测试光镊,MagneTherm细胞肿瘤电磁热疗测试分析系统
010-67529703
您现在的位置:
产品详情

CleanPlex® CMT Panel

  • 如果您对该产品感兴趣的话,可以
  • 产品名称:CleanPlex® CMT Panel
  • 产品型号:
  • 产品展商:Paragon Genomics CleanPlex
  • 产品文档:无相关文档
  • 发布时间:2020-03-28
  • 在线询价
简单介绍
CleanPlex® CMT Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing assay for examining the germline variants or mutations across 74
产品描述

Product Description

CleanPlex® CMT Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 74 genes associated with Charcot-Marie-Tooth Disease. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.

This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.

产品描述

CleanPlex®Charcot-Marie-Tooth Disease Panel是一种预先设计和定制的基于多重PCR /扩增子的靶向测序(NGS)分析方法,旨在检查与Charcot-Marie-DNA相关的74个基因的种系变异或突变。牙齿**。该小组针对这些基因的所有外显子区域和侧翼内含子序列。仅需10 ng DNA即可兼容测序就绪的文库,只需3个小时即可使用简化的工作流程进行准备。预先设计的面板经过计算机优化,可提供具有高目标性能和高覆盖均匀性的数据,以确保有效利用测序读数。

该产品是定做的。收到您的订单后,我们将合成面板,该套件将包含CleanPlex Multiplex PCR引物和CleanPlex Targeted Library Kit。可以分别订购CleanPlex索引PCR引物和CleanMag®磁珠,以完成从输入DNA到可测序的NGS文库的工作流程。


Storage Temperature

Store at -20 °C.

For Research Use Only. Not for use in diagnostic procedures.

Gene List: 
AARS, AIFM1, ARHGEF10, ATL1, ATP1A1, ATP7A, BSCL2, C12ORF65, COX6A1, CTDP1, DHTKD1, DNAJB2, DNM2, DNMT1, DYNC1H1, EGR2, ELP1, FBLN5, FGD4, FIG4, GAN, GARS, GDAP1, GJB1, GNB4, HADHB, HARS, HINT1, HK1, HSPB1, HSPB8, IGHMBP2, INF2, KARS, KIF1A, KIF1B, KIF5A, LITAF, LMNA, LRSAM1, MARS, MED25, MFN2, MME, MORC2, MPZ, MTMR2, NDRG1, NEFL, NGF, NTRK1, PDK3, PLEKHG5, PMP22, PRPS1, PRX, RAB7A, REEP1, RETREG1, SBF1, SBF2, SH3TC2, SLC12A6, SLC25A46, SPG11, SPTLC1, SPTLC2, TFG, TRIM2, TRPV4, TTR, VCP, WNK1, YARS

References: 
Pipis M, et al. Next-generation sequencing in Charcot-Marie-Tooth disease: opportunities and challenges. Nat Rev Neurol. 2019 Nov;15(11):644-656.

Morena J, et al. Charcot-Marie-Tooth: From Molecules to Therapy. Int J Mol Sci. 2019 Jul 12;20(14).

Vaeth S, et al. Genetic analysis of Charcot-Marie-Tooth disease in Denmark and the implementation of a next generation sequencing platform. Eur J Med Genet. 2019 Jan;62(1):1-8.

Li LX, et al. Improving molecular diagnosis of Chinese patients with Charcot-Marie-Tooth by targeted next-generation sequencing and functional analysis. Oncotarget. 2016 May 10;7(19):27655-64.

产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
  • 温馨提示:为规避购买风险,建议您在购买前务必确认供应商资质与产品质量。
  • 免责申明:以上内容为注册会员自行发布,若信息的真实性、合法性存在争议,平台将会监督协助处理,欢迎举报
关于我们| 易展动态| 易展荣誉| 易展服务| 易家文化| 英才集结号| 社会责任| 联系我们

备案号:粤ICP备11010883号| 公安机关备案号:44040202000312| 版权问题及信息删除: 0756-2183610  QQ: 服务QQ

Copyright?2004-2017  珠海市金信桥网络科技有限公司 版权所有

行业网站百强奖牌 搜索营销*有价值奖 中小企业电子商务**服务商
以上信息由企业自行提供,信息内容的真实性、准确性和合法性由相关企业负责,易展仪表展览网对此不承担任何保证责任。