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  • 入驻时间:2014-08-19
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Human Interleukin-29/Interferon Lambda 1, Carrier-Free[产品打印页面]

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  • 产品名称:Human Interleukin-29/Interferon Lambda 1, Carrier-Free
  • 产品型号:11826-1
  • 产品展商:PBL Assay Science
  • 产品文档:无相关文档
  • 发布时间:2018-10-25
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简单介绍
The IFN lambda gene family is composed of three distinct genes: IFN lambda 1 (IL-29), IFN lambda 2 (IL-28A) and IFN lambda 3 (IL-28B). All three are class II cytokine receptor ligands that are distinctly related to members of the IL-10 family and Type I family. Refer to the product specific datasheet for references associated with this information.
产品描述

Product Features: 
  • Recombinant Human Interleukin-29/IFN Lambda 1, carrier-free, expressed in mouse myeloma cells, NS0-derived
  • Exerts antiviral activity and up-regulation of MHC class I antigen expression
  • Plays an important role in host defenses against microbes

Full Product Name: Human Interleukin-29 (IL-29)/Interferon Lambda 1, carrier-free

Formulation Supplied lyophilized without a carrier protein
Molecular Weight Based on N-terminal sequencing, the mature recombinant IL-29 starts at Gly 20 and has a calculated molecular mass of 21.4 kDa. As a result of glycosylation, the recombinant monomer migrates as an approximately 26-35 kDa protein in SDS-PAGE under reducing conditions.
Source DNA sequence encoding the signal peptide from human CD33 was fused to the carboxyl terminally polyhistidine-tagged mature human IL-29 (Gly 20-Thr 200). The chimeric protein was expressed in a mouse myeloma cell line, NS0.
Purity Greater than 95%
Endotoxin level < 1 EU/μg
Bioactivity Human HepG2 cells infected with encephalomyocarditis virus, ED50 1-5 ng/ml
Storage For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
Synonyms Hu IL-29; Hu IFN-λ1

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