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- 产品名称:Human Interleukin-29/Interferon Lambda 1, Carrier-Free
- 产品型号:11826-1
- 产品展商:PBL Assay Science
- 产品文档:无相关文档
- 发布时间:2018-10-25
- 在线询价
简单介绍
The IFN lambda gene family is composed of three distinct genes: IFN lambda 1 (IL-29), IFN lambda 2 (IL-28A) and IFN lambda 3 (IL-28B). All three are class II cytokine receptor ligands that are distinctly related to members of the IL-10 family and Type I family. Refer to the product specific datasheet for references associated with this information.
产品描述
Product Features:
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Recombinant Human Interleukin-29/IFN Lambda 1, carrier-free, expressed in mouse myeloma cells, NS0-derived
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Exerts antiviral activity and up-regulation of MHC class I antigen expression
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Plays an important role in host defenses against microbes
Full Product Name: Human Interleukin-29 (IL-29)/Interferon Lambda 1, carrier-free
Formulation
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Supplied lyophilized without a carrier protein
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Molecular Weight
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Based on N-terminal sequencing, the mature recombinant IL-29 starts at Gly 20 and has a calculated molecular mass of 21.4 kDa. As a result of glycosylation, the recombinant monomer migrates as an approximately 26-35 kDa protein in SDS-PAGE under reducing conditions.
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Source
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DNA sequence encoding the signal peptide from human CD33 was fused to the carboxyl terminally polyhistidine-tagged mature human IL-29 (Gly 20-Thr 200). The chimeric protein was expressed in a mouse myeloma cell line, NS0.
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Purity
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Greater than 95%
Endotoxin level < 1 EU/μg
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Bioactivity
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Human HepG2 cells infected with encephalomyocarditis virus, ED50 1-5 ng/ml
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Storage
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For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
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Synonyms
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Hu IL-29; Hu IFN-λ1
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