2'-5'-Oligoadenylate Synthetase 1 (OAS1) Antibody abx032742 上海玉博生物科技有限公司

2'-5'-Oligoadenylate Synthetase 1 (OAS1) Antibody

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产品名称：2'-5'-Oligoadenylate Synthetase 1 (OAS1) Antibody
产品型号：abx032742
产品展商：abbexa
产品文档：无相关文档

简单介绍

2'-5'-Oligoadenylate Synthetase 1 (OAS1) Antibody

产品描述

OAS1 is an interferon inducible protein that may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. It binds double-stranded RNA and polymerizes ATP into PPP (A2'P5'A) N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. This protein is associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.

Target	2'-5'-Oligoadenylate Synthetase 1 (OAS1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 302-330 amino acids from the C-terminal region of human OAS1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P00973 (UniProt, ExPASy)
UniProt Entry Name	OAS1_HUMAN
NCBI Accession	NP_001027581.1 NP_002525.2 NP_058132.2
KEGG	hsa:4938
String	9606.ENSP
Molecular Weight	Calculated MW: 46 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 2'-5'-Oligoadenylate Synthetase 1 (OAS1)

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2'-5'-Oligoadenylate Synthetase 1 (OAS1) Antibody