Alsin (ALS2) Antibody abx003718 上海玉博生物科技有限公司

Alsin (ALS2) Antibody

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产品名称：Alsin (ALS2) Antibody
产品型号：abx003718
产品展商：abbexa
产品文档：无相关文档

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Alsin (ALS2) Antibody

产品描述

ALS2 Antibody is a Rabbit Polyclonal antibody against ALS2. The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Alsin (ALS2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ALS2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q96Q42 (UniProt, ExPASy)
UniProt Secondary AC	Q53TT1, Q53TV2, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9
UniProt Entry Name	ALS2_HUMAN
Gene Symbol	ALS2
GeneID	57679
NCBI Accession	NP_065970.2
KEGG	hsa:57679
String	9606.ENSP
Molecular Weight	Calculated MW: 184 kDa Observed MW: 174 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Alsin (ALS2)

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Alsin (ALS2) Antibody