Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A) Antibody abx004240 上海玉博生物科技有限公司

Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A) Antibody

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产品名称：Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A) Antibody
产品型号：abx004240
产品展商：abbexa
产品文档：无相关文档

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Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A) Antibody

产品描述

SCNN1A Antibody is a Rabbit Polyclonal antibody against SCNN1A. Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Target	Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 105-225 of human SCNN1A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P23458 (UniProt, ExPASy)
UniProt Secondary AC	Q59GQ2, Q9UD26
UniProt Entry Name	JAK1_HUMAN
Gene Symbol	JAK1
GeneID	6337
NCBI Accession	NP_001029.1
KEGG	hsa:3716
String	9606.ENSP
Molecular Weight	Calculated MW: 76 kDa Observed MW: 75 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A)

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Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A) Antibody