Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody abx027970 上海玉博生物科技有限公司

Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody

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产品名称：Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody
产品型号：abx027970
产品展商：abbexa
产品文档：无相关文档

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Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody

产品描述

ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.

Target	Aldehyde Dehydrogenase, Mitochondrial (ALDH2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human ALDH2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P05091 (UniProt, ExPASy)
UniProt Secondary AC	B4DW54, E7EUE5, Q03639, Q6IB13, Q6IV71
UniProt Entry Name	ALDH2_HUMAN
NCBI Accession	NP_000681.2 NP_001191818.1
KEGG	hsa:217
String	9606.ENSP
Molecular Weight	Calculated MW: 56.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aldehyde Dehydrogenase, Mitochondrial (ALDH2)

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Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody