Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody abx025191 上海玉博生物科技有限公司

Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody

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产品名称：Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody
产品型号：abx025191
产品展商：abbexa
产品文档：无相关文档

简单介绍

Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody

产品描述

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.

Target	Aldehyde Dehydrogenase, Mitochondrial (ALDH2)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC, FCM
Host	Mouse
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Human ALDH2 recombinant protein.
Isotype	IgG₁ Kappa
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P05091 (UniProt, ExPASy)
UniProt Secondary AC	B4DW54, E7EUE5, Q03639, Q6IB13, Q6IV71
UniProt Entry Name	ALDH2_HUMAN
KEGG	hsa:217
String	9606.ENSP
Molecular Weight	Calculated MW: 56.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aldehyde Dehydrogenase, Mitochondrial (ALDH2)

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Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody