Anti-phospho-ATG9A(Ser735)/FITC抗体 Anti-phospho-ATG9A(Ser735)/FITC

Anti-phospho-ATG9A(Ser735)/FITC抗体

产品编号YB-5199R-FITC

英文名称Anti-phospho-ATG9A(Ser735)/FITC

中文名称FITC标记的磷酸化自噬相关蛋白9A抗体

别    名APG9 autophagy 9-like 1; APG9 like 1; APG9-like 1; APG9L1; ATG9; ATG9 autophagy related 9 homolog A; ATG9 autophagy related 9 homolog A (S. cerevisiae); ATG9A; ATG9A_HUMAN; Autophagy 9-like 1 protein; Autophagy related protein 9A; Autophagy-related protein 9A; mATG9; MGD3208; OTTHUMP; OTTHUMP; OTTHUMP; OTTHUMP.

Anti-phospho-ATG9A(Ser735)/FITC抗体

说 明 书100ul  

产品类型磷酸化抗体

研究领域肿瘤  心血管  细胞生物  **学  神经生物学  信号转导  细胞凋亡  线粒体  泛素  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Pig, Cow,

产品应用IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量94kDa

Anti-phospho-ATG9A(Ser735)/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

*** 原KLH conjugated Synthesised phosphopeptide derived from human ATG9A around the phosphorylation site of Ser735

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-phospho-ATG9A(Ser735)/FITC抗体

产品介绍background:

Plays a role in autophagy. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and FAM48A.

Function:

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.

Subunit:

Interacts with SUPT20H.

Subcellular Location:

Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.Anti-phospho-ATG9A(Ser735)/FITC抗体 Late endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation-induced redistribution depends on ULK1, ATG13, as well as SH3GLB1.

Similarity:

Belongs to the ATG9 family.

Database links:

UniProtKB/Swiss-Prot: Q7Z3C6.3

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.