Anti-BLMH/FITC抗体 Anti-BLMH/FITC

点击查看大图

产品价格： < 面议

产品型号：Anti-BLMH/FITC

品牌：科研抗体

公司名称：上海钰博生物科技有限公司

所在地：上海松江

浏览次数：128 次

立即询价在线咨询

产品简介

Anti-BLMH/FITC抗体和抗原之间的结合具有高度的特异性，**组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来，以此作为抗原或半抗原，Anti-BLMH/FITC抗体通过**动物后获得特异性的抗体，再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的，因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来，以其达到对组织或细胞中的未知抗原进行定性，定位或定量的研究。

产品详细信息

Anti-BLMH/FITC抗体

产品编号YB-11654R-FITC

英文名称Anti-BLMH/FITC

中文名称FITC标记的博莱霉素水解酶抗体

别名BH; bleomycin hydrolase; BLM hydrolase; BMH; EC 3.4.22.40; BLMH_HUMAN.

Anti-BLMH/FITC抗体

说明书100ul

研究领域神经生物学 Alzheimer's

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用ICC=1:50-200 IF=1:50-200

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分子量53kDa

Anti-BLMH/FITC抗体性状Lyophilized or Liquid

浓度1mg/ml

*** 原KLH conjugated synthetic peptide derived from human BLMH (308-400aa)

亚型IgG

纯化方法affinity purified by Protein A

储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-BLMH/FITC抗体

产品介绍background:

Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008].

Function:

BLMH is a member of the peptidase C1 family and exists as a homohexamer. While its normal physiological function is not known, it protects normal and malignant cells from the glycopeptide antitumor drug BLM. It inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine and also Anti-BLMH/FITC抗体shows general aminopeptidase activity. The specificity varies but amino acid arylamides of Met, Leu and Ala are preferred.

Subunit:

Homohexamer.

Subcellular Location:

Cytoplasmic

Tissue Specificity:

Similarity:

Belongs to the peptidase C1 family.

Database links:

UniProtKB/Swiss-Prot: Q13867.

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.