Anti-CK5+CK6/FITC抗体 Anti-CK5+CK6/FITC
产品简介
Anti-CK5+CK6/FITC抗体和抗原之间的结合具有高度的特异性,**组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来,以此作为抗原或半抗原,Anti-CK5+CK6/FITC抗体通过**动物后获得特异性的抗体,再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的,因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来,以其达到对组织或细胞中的未知抗原进行定性,定位或定量的研究。
产品详细信息
Anti-CK5+CK6/FITC抗体
产品编号YB20824R-FITC
英文名称Anti-CK5+CK6/FITC
中文名称FITC标记的细胞角蛋白5+6抗体
别 名CK5+6; Cytokeratin 5; Keratin, type II cytoskeletal 5; CK-5; Keratin-5; K5; 58 kDa cytokeratin; KRT5; CK 5; DDD; EBS 2; EBS2; K5; Keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); Keratin 5; Keratin Type II Cytoskeletal 5; Keratin5; KRT 5; KRT 5A; KRT5.KRT6A; CK6A; CK6B; CK6C; CK6D; CK 6E; K6A; K6C; K6D; KRT6C; Cytokeratin 6a; Cytokeratin 6B; Cytokeratin 6C; Cytokeratin 6D; Cytokeratin 6E; Cytokeratin6; k6a keratin; K6B; K6b keratin; K6c keratin; K6d keratin; K6e keratin; k6hf; Keratin 6 isoform K6e; Keratin 6C; Keratin 6E; Keratin K6h; Keratin type II cytosk
Anti-CK5+CK6/FITC抗体
说 明 书100ug
研究领域肿瘤
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse,
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量62/60kDa
Anti-CK5+CK6/FITC抗体性 状Lyophilized or Liquid
浓 度2mg/1ml
*** 原KLH conjugated synthetic peptide derived from human CK5+CK6
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-CK5+CK6/FITC抗体
产品介绍background:
Keratins 5, 6 are members of type II keratins family that are specifically expressed in the inner root sheath of hair follicles. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Keratin 18 is memeber of the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family.
Subunit:
Subcellular Location:
DISEASE:
Similarity:
Database links:
Entrez Gene: 3852 Human
Entrez Gene: 3853 Human
Anti-CK5+CK6/FITC抗体Entrez Gene: 3854 Human
Omim: 148040 Human
SwissProt: P02538 Human
SwissProt: P04259 Human
SwissProt: P13647 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞角蛋白5&6是高分子量细胞角蛋白,分子量分别为58KDa和56KDa。其表达在皮肤的基底细胞、棘层细胞和部分前列腺基底细胞。主要用于间皮瘤和腺癌的鉴别诊断,并可辅助诊断前列腺良恶性病变。