肝再生磷酸酯酶1抗体 PRL1

肝再生磷酸酯酶1抗体

规格：1mg/1ml

英文名： PRL1

别名： HH 72; HH72; Hypothetical protein DKFZp779M0721; PRL 1; PRL-1; PRL1; Protein tyrosine phosphatase PTPCAAX1; Protein tyrosine phosphatase type IVA 1; Protein tyrosine phosphatase type IVA member 1; Pro

分子量： 25kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

**原：KLH conjugated synthetic peptide derived from human PTP4A1(2

交叉反应：Human,

细胞定位：

肝再生磷酸酯酶1抗体产品介绍：background: PTP4A1 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. Function: Opiorphin is an endogenous inhibitor of neprilysin and aminopeptidase N. Inhibits the breakdown of substance P, Mca-BK2肝再生磷酸酯酶1抗体 and Met-enkephalin by neprilysin in vitro with IC(50) values of 29 uM, 33 uM and 33 uM respectively. Inhibits the breakdown of Ala-pNA by aminopeptidase N in vitro with an IC(50) of 65 uM. Has a potent analgesic effect when administered to rats by intravenous injection. Subunit: Secreted. Subcellular Location: Abundantly expressed in lacrimal gland where it found in the secretory endpieces. Also expressed 肝再生磷酸酯酶1抗体at modest levels in the submandibular gland. Similarity: Belongs to the PROL1/PROL3 family. Database links: Entrez Gene: 533951 Cow Entrez Gene: 5356 Human Entrez Gene: 53317 Mouse Entrez Gene: 60376 Rat Omim: 605961 Human SwissProt: Q2KID6 Cow SwissProt: O43660 Human SwissProt: Q922V4 Mouse SwissProt: Q9WUC8 Rat Unigene: 249996 Human Unigene: 286349 Mouse Unigene: 44181 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

肝再生磷酸酯酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：肿瘤  **学  信号转导  转录调节因子  激酶和磷酸酶  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid