产品名称：Anti-ACVR2A抗体

Cat. Number:

YB0804R

Quantity size:

0.1ml

Concentration:

Anti-ACVR2A抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Anti-ACVR2A抗体Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. Activin has been suggested to be an autocrine/paracrine regulator in the human placenta. The presence of ACVR2 mRNA has been deomnstrated in human trophoblast cells and there is also evidence of expression of the gene in human brain and ovary.

Also known as:

Anti-ACVR2A抗体Activin receptor 2A; Activin receptor type 2A; ACTR 2; ACTR IIA; ACTR2; ActRIIa; Acvr 2; Acvr 2A; Acvr2; Acvr2a; OTTHUMP00000197918; ACVR2A; Activin receptor type-2A.

Specificity:

Storage:

Anti-ACVR2A抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Anti-ACVR2A抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
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