企业信息
第7年
- 入驻时间: 2015-11-06
- 联系人:顾磊
- 电话:021-60514606
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联系时,请说明易展网看到的
- Email:shybio@126.com
产品分类
产品详情
简单介绍:
Anti-ADAMTS5抗体供应商为您提供抗体的售前、售中、售后服务,现货供应,保证实验结果,无效可以免费退换,广泛应用于IHC、WB、 IF、IP、ELISA,质量保证,另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂,Anti-ADAMTS5抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍:
Rabbit Anti-ADAMTS5
Cat. Number:
YB3573R
Quantity size:
0.1ml
Concentration:
Anti-ADAMTS5抗体1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Anti-ADAMTS5抗体ADAMTS5 was first described as ADAMTS5, a protein elevated in mice during the peri-implantion period. At the same time, another group identified Aggrecanase 11, a protein elevated in arthritic synovium. The name was later changed to ADAMTS5. ADAMTS5 is expressed in human and mouse. It has been found in heart, lung, cervix, uterus, ovary, brain, cartilage, and numerous other tissues, as well as chondroblastoma cell lines. Initial observations indicated a role for ADAMTS5 in aggrecan cleavage and cartilage destruction, especially in arthritis, and potentially a role in embryo implantation. ADAMTS5 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to efficiently cleave Aggrecan. In addition to the metalloprotease domain, ADAMTS5 has a propeptide domain, a prohormone convertase (PC, furin) cleavage site, a cysteine-rich domain, a spacer domain, and two thrombospondin-1 like domains. ADAMTS5 is inhibited by the endogenous MMP inhibitors (TIMP1, 2, 3, and 4) but most efficiently by TIMP3. Unlike many of the ADAMs proteases, ADAMTS5 does not have a transmembrane domain, and is a secreted protein. Full length ADAMTS5 is a 930 amino acid protein with a predicted molecular mass is 101.7 kDa, but glycosylation and the abundance of cysteine residues gives ADAMTS5 a greater apparent molecular weight on reduced SDS PAGE gels. When ADAMTS5 is secreted, it is cleaved at the furin cleavage site (predicted molecular mass 73.2 kDa) and then further cleaved to generate a range of smaller forms.
Also known as:
Anti-ADAMTS5抗体ADAMTS5; A disintegrin and metalloproteinase with thrombospondin motifs 5; A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 5; A Disintigrin And Metalloproteinase with ThromboSpondin motif-5; ADAM metallopeptidase with thrombospondin type 1 motif 5; ADAM TS 11; ADAM TS 5; ADAM TS5; ADAMTS 11; ADAMTS 5; ADAMTS11; ADMP 2; ADMP2; Aggrecanase 2; aggrecanase-2; FLJ36738; Implantin; ThromboSpondin motif-5.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human Aggrecan 2.
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Predicted Molecular Weight: 102kDa.
Storage:
Anti-ADAMTS5抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-ADAMTS5抗体ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.yb432Mu01 皮肤桥蛋白(DPT)多克隆抗体 Polyclonal Antibody to Dermatopontin (DPT) Mus musculus (Mouse)
yb436Hu01 牙本质涎磷蛋白(DSPP)多克隆抗体 Polyclonal Antibody to Dentin Sialophosphoprotein (DSPP) Homo sapiens (Human)
yb438Hu01 迪格弗梅尔基奥尔克劳森综合征蛋白(DYM)多克隆抗体 Polyclonal Antibody to Dymeclin (DYM) Homo sapiens (Human)
yb440Hu01 脱氧胞苷激酶(DCK)多克隆抗体 Polyclonal Antibody to Deoxycytidine Kinase (DCK) Homo sapiens (Human)
yb442Hu01 双肾上腺皮质**(DCX)多克隆抗体 Polyclonal Antibody to Doublecortin (DCX) Homo sapiens (Human)
yb442Mu01 双肾上腺皮质**(DCX)多克隆抗体 Polyclonal Antibody to Doublecortin (DCX) Mus musculus (Mouse)
yb442Ra01 双肾上腺皮质**(DCX)多克隆抗体 Polyclonal Antibody to Doublecortin (DCX) Rattus norvegicus (Rat)
yb445Hu01 奇异**素(DYSF)多克隆抗体 Polyclonal Antibody to Dysferlin (DYSF) Homo sapiens (Human)
yb448Hu01 肌营养**蛋白关联糖蛋白1(DAG1)多克隆抗体 Polyclonal Antibody to Dystrophin Associated Glycoprotein 1 (DAG1) Homo sapiens (Human)
yb448Mu01 肌营养**蛋白关联糖蛋白1(DAG1)多克隆抗体 Polyclonal Antibody to Dystrophin Associated Glycoprotein 1 (DAG1) Mus musculus (Mouse)
yb450Hu01 细胞外基质蛋白1(ECM1)多克隆抗体 Polyclonal Antibody to Extracellular Matrix Protein 1 (ECM1) Homo sapiens (Human)
yb450Mu01 细胞外基质蛋白1(ECM1)多克隆抗体 Polyclonal Antibody to Extracellular Matrix Protein 1 (ECM1) Mus musculus (Mouse)
yb459Mu01 内磺肽α(ENSα)多克隆抗体 Polyclonal Antibody to Endosulfine Alpha (ENSa) Mus musculus (Mouse)
yb463Hu01 内皮细胞特异分子1(ESM1)多克隆抗体 Polyclonal Antibody to Endothelial Cell Specific Molecule 1 (ESM1) Homo sapiens (Human)
yb466Hu01 巢蛋白(NID)多克隆抗体 Polyclonal Antibody to Nidogen (NID) Homo sapiens (Human)
yb468Hu01 脂肪酸去饱和酶1(FADS1)多克隆抗体 Polyclonal Antibody to Fatty Acid Desaturase 1 (FADS1) Homo sapiens (Human)
yb468Ra01 脂肪酸去饱和酶1(FADS1)多克隆抗体
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.yb432Mu01 皮肤桥蛋白(DPT)多克隆抗体 Polyclonal Antibody to Dermatopontin (DPT) Mus musculus (Mouse)
yb436Hu01 牙本质涎磷蛋白(DSPP)多克隆抗体 Polyclonal Antibody to Dentin Sialophosphoprotein (DSPP) Homo sapiens (Human)
yb438Hu01 迪格弗梅尔基奥尔克劳森综合征蛋白(DYM)多克隆抗体 Polyclonal Antibody to Dymeclin (DYM) Homo sapiens (Human)
yb440Hu01 脱氧胞苷激酶(DCK)多克隆抗体 Polyclonal Antibody to Deoxycytidine Kinase (DCK) Homo sapiens (Human)
yb442Hu01 双肾上腺皮质**(DCX)多克隆抗体 Polyclonal Antibody to Doublecortin (DCX) Homo sapiens (Human)
yb442Mu01 双肾上腺皮质**(DCX)多克隆抗体 Polyclonal Antibody to Doublecortin (DCX) Mus musculus (Mouse)
yb442Ra01 双肾上腺皮质**(DCX)多克隆抗体 Polyclonal Antibody to Doublecortin (DCX) Rattus norvegicus (Rat)
yb445Hu01 奇异**素(DYSF)多克隆抗体 Polyclonal Antibody to Dysferlin (DYSF) Homo sapiens (Human)
yb448Hu01 肌营养**蛋白关联糖蛋白1(DAG1)多克隆抗体 Polyclonal Antibody to Dystrophin Associated Glycoprotein 1 (DAG1) Homo sapiens (Human)
yb448Mu01 肌营养**蛋白关联糖蛋白1(DAG1)多克隆抗体 Polyclonal Antibody to Dystrophin Associated Glycoprotein 1 (DAG1) Mus musculus (Mouse)
yb450Hu01 细胞外基质蛋白1(ECM1)多克隆抗体 Polyclonal Antibody to Extracellular Matrix Protein 1 (ECM1) Homo sapiens (Human)
yb450Mu01 细胞外基质蛋白1(ECM1)多克隆抗体 Polyclonal Antibody to Extracellular Matrix Protein 1 (ECM1) Mus musculus (Mouse)
yb459Mu01 内磺肽α(ENSα)多克隆抗体 Polyclonal Antibody to Endosulfine Alpha (ENSa) Mus musculus (Mouse)
yb463Hu01 内皮细胞特异分子1(ESM1)多克隆抗体 Polyclonal Antibody to Endothelial Cell Specific Molecule 1 (ESM1) Homo sapiens (Human)
yb466Hu01 巢蛋白(NID)多克隆抗体 Polyclonal Antibody to Nidogen (NID) Homo sapiens (Human)
yb468Hu01 脂肪酸去饱和酶1(FADS1)多克隆抗体 Polyclonal Antibody to Fatty Acid Desaturase 1 (FADS1) Homo sapiens (Human)
yb468Ra01 脂肪酸去饱和酶1(FADS1)多克隆抗体