产品详情
简单介绍：
Anti-ETV4 Antibody
详情介绍：
Overview
| Name: | Anti-ETV4 Antibody See all ETV4 primary antibodies
|
| Description: | Rabbit polyclonal antibody to ETV4 |
| Specificity: | ETV4 pAb detects endogenous levels of ETV4 protein. |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant full length Human ETV4. |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Molecular Weight: | ~ 54 kDa |
| Purity: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
| Product Form: | 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol. |
Target
| Function: | Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'. |
| Sequence Similarities: | Belongs to the ETS family. |
| Post-Translational Modification: | Sumoylated; enhanced upon ERK/MAP kinase pathway activation, it positively regulates the transcriptional activator capacity. Sumoylation at Lys-96 probably requires phosphorylation at Ser-101. Transiently polysumoylated and desumoylated by SENP1. Sumoylation is a prerequisite to polyubiquitination which in turn increases proteasomal-mediated degradation. Probably polyubiquitinated by RNF4 and deubiquitinated by USP2. |
| Cellular Location: | Nucleus. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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