产品详情
简单介绍：
Anti-F10 Antibody
详情介绍：
Overview
| Name: | Anti-F10 Antibody See all F10 primary antibodies
|
| Description: | Rabbit polyclonal antibody to F10. |
| Applications: | WB, IHC, IF |
| Dilutions: | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100. |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant protein of human F10. |
| Protein Length: | 488 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Affinity purification. |
| Product Form: | Liquid |
| Formulation: | Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. |
| Tissue Specificity: | Plasma; synthesized in the liver. |
| Involvement in Disease: | Factor X deficiency: A hemorrhagic disease with variable presentation. Affected individuals can manifest prolonged nasal and mucosal hemorrhage, menorrhagia, hematuria, and occasionally hemarthrosis. Some patients do not have clinical bleeding diathesis. |
| Sequence Similarities: | Belongs to the peptidase S1 family. |
| Post-Translational Modification: | The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium. |
| Cellular Location: | Secreted. |
相关文章
