产品详情
简单介绍：
Anti-F11R Antibody
详情介绍：
Overview
| Name: | Anti-F11R Antibody See all F11R primary antibodies
|
| Description: | Goat polyclonal antibody to F11R. |
| Applications: | ELISA, WB |
| Reactivity: | Human |
| Immunogen: | Synthetic peptide corresponding to Human F11R (C terminal). |
| Sequence: | C-QPSARSEGEFKQTS |
| Host: | Goat |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Unconjugated |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 100 µg at 0.5 mg/ml. |
| Product Form: | Liquid |
| Formulation: | Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Target
| Function: | Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840). |
| Tissue Specificity: | Expressed in endothelium, epithelium and leukocytes (at protein level). |
| Sequence Similarities: | Belongs to the immunoglobulin superfamily. |
| Post-Translational Modification: | N-glycosylated. |
| Cellular Location: | Cell junction > Tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells. |
| Database Links: |
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| Synonyms: | |
| Information: | Target information shown above is from the UniProt Consortium. |
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