Anti-5HT1A antibody (200-250) (STJ500000) STJ500000-100 上海玉博生物科技有限公司

Anti-5HT1A antibody (200-250) (STJ500000)

简单介绍

Anti-5HT1A antibody (200-250) (STJ500000)

产品描述

Host:	Rabbit
Applications:	ELISA/IP/WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.5-1.5 µg/µl
Dilution Range:	WB: 1:2, 500-1:5, 000 DB: 1:50, 000 ELISA: 1:50, 000 IP: 1:200
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Htr1a
Gene ID:	24473
Uniprot ID:	5HT1A_RAT
Immunogen Region:	200-250
Immunogen:	Synthetic peptide corresponding to amino acids within region 200-250 on rat 5-hydroxytryptamine receptor 1A protein.

Tissue Specificity	Detected in hypothalamus, mesencephalon, amygdala, medulla, thalamus, septum and hippocampus.
Function	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Protein Name	5-Hydroxytryptamine Receptor 1a 5-Ht-1a 5-Ht1a Serotonin Receptor 1a
Database Links	Reactome: R-RNO-390666
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Cell Projection Dendrite
Alternative Antibody Names	Anti-5-Hydroxytryptamine Receptor 1a antibody Anti-5-Ht-1a antibody Anti-5-Ht1a antibody Anti-Serotonin Receptor 1a antibody Anti-Htr1a antibody Anti-5ht1a antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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