Anti-5HT1B antibody (160-260) (STJ500003) STJ500003-100 上海玉博生物科技有限公司

Anti-5HT1B antibody (160-260) (STJ500003)

简单介绍

Anti-5HT1B antibody (160-260) (STJ500003)

产品描述

Host:	Rabbit
Applications:	ELISA/IP/WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-5HT1B (160-260) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.5-1.5 µg/µl
Dilution Range:	WB: 1:2, 500-1:5, 000 DB: 1:50, 000 ELISA: 1:50, 000 IP: 1:200
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Htr1b
Gene ID:	15551
Uniprot ID:	5HT1B_MOUSE
Immunogen Region:	160-260
Immunogen:	Synthetic peptide taken within amino acid region 160-260 on rat 5HT1B

Tissue Specificity	Predominantly expressed in striatum and Purkinje cells.
Post Translational Modifications	Phosphorylated. Palmitoylated.
Function	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
Protein Name	5-Hydroxytryptamine Receptor 1b 5-Ht-1b 5-Ht1b Serotonin Receptor 1b
Database Links	Reactome: R-MMU-390666 Reactome: -MMU-418594
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-5-Hydroxytryptamine Receptor 1b antibody Anti-5-Ht-1b antibody Anti-5-Ht1b antibody Anti-Serotonin Receptor 1b antibody Anti-Htr1b antibody Anti-5ht1b antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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