Active Mouse CSF-1/M-CSF protein (Recombinant) (C-His) (STJP002734) STJP002734 上海玉博生物科技有限公司

Active Mouse CSF-1/M-CSF protein (Recombinant) (C-His) (STJP002734)

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产品名称：Active Mouse CSF-1/M-CSF protein (Recombinant) (C-His) (STJP002734)
产品型号：STJP002734
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Active Mouse CSF-1/M-CSF protein (Recombinant) (C-His) (STJP002734)

产品描述

Host:	HEK293 cells
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Active Mouse CSF-1/M-CSF-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity:	1.Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 0.1-0.4 ng/mL, corresponding to a specific activity of 2.5×106-1.0×107units/mg.2.Measured in a cell proliferat

Gene Symbol:	Csf1
Gene ID:	12977
Uniprot ID:	CSF1_MOUSE
Immunogen Region:	Met1-Glu262
Immunogen:	Active Recombinant Mouse CSF-1/M-CSF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Glu262) of mouse M-CSF/CSF-1 (Accession #NP_031804.3.) fused with a 6×His tag at the C-terminus.

Function	Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Protein Name	Macrophage Colony-Stimulating Factor 1 Csf-1 Mcsf Proteoglycan Macrophage Colony-Stimulating Factor Pg-M-Csf Cleaved Into - Processed Macrophage Colony-Stimulating Factor 1 - Macrophage Colony-Stimulating Factor 1 43 Kda Subunit
Database Links	Reactome: R-MMU-381426 Reactome: -MMU-449836 Reactome: -MMU-8957275
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Processed Macrophage Colony-Stimulating Factor 1: Secreted Extracellular Space
Alternative Protein Names	Macrophage Colony-Stimulating Factor 1 protein Csf-1 protein Mcsf protein Proteoglycan Macrophage Colony-Stimulating Factor protein Pg-M-Csf Cleaved Into - Processed Macrophage Colony-Stimulating Factor 1 - Macrophage Colony-Stimulating Factor 1 43 Kda Subunit protein Csf1 protein Csfm protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Active Mouse CSF-1/M-CSF protein (Recombinant) (C-His) (STJP002734)