5HT1B Blocking Peptide for STJ500004 peptide (STJ503613) STJ503613-250 上海玉博生物科技有限公司

5HT1B Blocking Peptide for STJ500004 peptide (STJ503613)

简单介绍

5HT1B Blocking Peptide for STJ500004 peptide (STJ503613)

产品描述

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	5HT1B Blocking Peptide for STJ500004 is synthetically produced from the 160-260 sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Htr1b
Gene ID:	15551
Uniprot ID:	5HT1B_MOUSE
Immunogen Region:	160-260
Specificity:	This blocking peptide is recommended for use in combination with 5HT1B antibody, STJ500004
Immunogen:	Synthetic peptide taken within amino acid region 160-260 on rat 5HT1B

Tissue Specificity	Predominantly expressed in striatum and Purkinje cells.
Post Translational Modifications	Phosphorylated. Palmitoylated.
Function	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
Peptide Name	5-Hydroxytryptamine Receptor 1b 5-Ht-1b 5-Ht1b Serotonin Receptor 1b
Database Links	Reactome: R-MMU-390666 Reactome: -MMU-418594
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Peptide Names	5-Hydroxytryptamine Receptor 1b protein 5-Ht-1b protein 5-Ht1b protein Serotonin Receptor 1b protein Htr1b protein 5ht1b protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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