ABHD2 Positive Control for STJ500017 peptide (STJ505473) STJ505473-5 上海玉博生物科技有限公司

ABHD2 Positive Control for STJ500017 peptide (STJ505473)

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产品名称：ABHD2 Positive Control for STJ500017 peptide (STJ505473)
产品型号：STJ505473-5
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

ABHD2 Positive Control for STJ500017 peptide (STJ505473)

产品描述

Applications:	WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	ABHD2 Positive Control for STJ500017 is synthetically produced from the sequence and is suitable for use in western blot applications.

Formulation:	Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range:	WB: 1:500
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Abhd2
Gene ID:	54608
Uniprot ID:	ABHD2_MOUSE
Specificity:	This is positive control is recommended for use in combination with ABHD2 antibody STJ500017.

Tissue Specificity	Widely expressed with higher expression in testis. Expressed by vascular smooth muscle cells, non vascular smooth muscle cells and heart.
Function	Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation. Involved in acrosomal reaction (Probable). May also play a role in smooth muscle cells migration.
Peptide Name	Monoacylglycerol Lipase Abhd2 2-Arachidonoylglycerol Hydrolase Abhydrolase Domain-Containing Protein 2 Acetylesterase Lung Alpha/Beta Hydrolase 2 Mmlabh2 Triacylglycerol Lipase
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein Cytoplasmic Vesicle Secretory Vesicle Acrosome Membrane Absent From The Sperm Flagellum
Alternative Peptide Names	Monoacylglycerol Lipase Abhd2 protein 2-Arachidonoylglycerol Hydrolase protein Abhydrolase Domain-Containing Protein 2 protein Acetylesterase protein Lung Alpha/Beta Hydrolase 2 protein Mmlabh2 protein Triacylglycerol Lipase protein Abhd2 protein Labh-2 protein Labh2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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ABHD2 Positive Control for STJ500017 peptide (STJ505473)