Anti-A1CF antibody (50-120) (STJ115054) STJ115054 上海玉博生物科技有限公司

Anti-A1CF antibody (50-120) (STJ115054)

简单介绍

Anti-A1CF antibody (50-120) (STJ115054)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-A1CF (50-120) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IHC-P 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	A1CF
Gene ID:	29974
Uniprot ID:	A1CF_HUMAN
Immunogen Region:	50-120
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 50-120 of human A1CF (NP_055391.2).
Immunogen Sequence:	APPERGCEIFIGKLPRDLFE DELIPLCEKIGKIYEMRMMM DFNGNNRGYAFVTFSNKVEA KNAIKQLNNYE

Tissue Specificity	Widely expressed with highest levels in brain, liver, pancreas, colon and spleen.
Function	Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay.
Protein Name	Apobec1 Complementation Factor Apobec1-Stimulating Protein
Database Links	Reactome: R-HSA-72200 Reactome: R-HSA-75094
Cellular Localisation	Nucleus Endoplasmic Reticulum Cytoplasm Predominantly Nuclear Where It Localizes To Heterochromatin Also Cytoplasmic Where It Is Found At The Outer Surface Of The Endoplasmic Reticulum Shuttles Between The Nucleus And Cytoplasm May Be Transported Into The Nucleus By The Nuclear Import Protein Tnpo2/Trn2 Or By Apobec1
Alternative Antibody Names	Anti-Apobec1 Complementation Factor antibody Anti-Apobec1-Stimulating Protein antibody Anti-A1CF antibody Anti-ACF antibody Anti-ASP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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