Anti-A2M antibody (1100-1180 aa) (STJ93980) STJ93980 上海玉博生物科技有限公司

Anti-A2M antibody (1100-1180 aa) (STJ93980)

简单介绍

Anti-A2M antibody (1100-1180 aa) (STJ93980)

产品描述

Host:	Rabbit
Applications:	IHC/IF/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Alpha-2-macroglobulin (1100-1180 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	A2M
Gene ID:	2
Uniprot ID:	A2MG_HUMAN
Immunogen Region:	1100-1180 aa
Specificity:	Macroglobulin Alpha-2 Polyclonal Antibody detects endogenous levels of Macroglobulin Alpha-2 protein.
Immunogen:	Synthesized peptide derived from Macroglobulin Alpha-2 at the amino acid range 1100-1180

Function	Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
Protein Name	Alpha-2-Macroglobulin Alpha-2-M C3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 5
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-140837 Reactome: R-HSA-1474228 Reactome: R-HSA-8963896
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Alpha-2-Macroglobulin antibody Anti-Alpha-2-M antibody Anti-C3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 5 antibody Anti-A2M antibody Anti-CPAMD5 antibody Anti-FWP007 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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