AGE Blocking Peptide for STJ500054 peptide (STJ503632) STJ503632-250 上海玉博生物科技有限公司

AGE Blocking Peptide for STJ500054 peptide (STJ503632)

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产品名称：AGE Blocking Peptide for STJ500054 peptide (STJ503632)
产品型号：STJ503632-250
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

AGE Blocking Peptide for STJ500054 peptide (STJ503632)

产品描述

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	AGE Blocking Peptide for STJ500054 is synthetically produced from the sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Specificity:	This blocking peptide is recommended for use in combination with AGE antibody, STJ500054
Immunogen:	Purified glycated ribonuclease corresponding to AGE. Glycated ribonuclease (RNase) prepared by incubating RNase with glucose at 37⁰C for several months.

Background

Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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AGE Blocking Peptide for STJ500054 peptide (STJ503632)