Anti-ABCA8 antibody (C-Term) (STJ71602) STJ71602-100 上海玉博生物科技有限公司

Anti-ABCA8 antibody (C-Term) (STJ71602)

简单介绍

Anti-ABCA8 antibody (C-Term) (STJ71602)

产品描述

Host:	Goat
Applications:	Pep-ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-ABCA8 (C-Term) is suitable for use in ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	ELISA-antibody detection limit dilution 1:4000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	ABCA8
Gene ID:	10351
Uniprot ID:	ABCA8_HUMAN
Immunogen Region:	C-Term
Accession Number:	NP_009099.1
Specificity:	This antibody is expected to cross-react with the highly similar Human ABCA9, since the immunizing peptide differs from ABCA9 with only one residue (F8).
Immunogen Sequence:	KEQELGDFEEDFD

Function	Isoform 1: Catalyzes ATP-dependent import of organic anions such as taurocholate and estrone sulfate. In vitro, also imports ochratoxin A. Also mediates cholesterol efflux independent of apolipoprotein, and plays a role in sphingomyelin production in oligodendrocytes. Isoform 3: Catalyzes ATP-dependent efflux of cholesterol and taurocholate. Interaction with ABCA1 potentiates cholesterol efflux to lipid-free APOA1, which regulates high-density lipoprotein cholesterol levels.
Protein Name	Abc-Type Organic Anion Transporter Abca8 Atp-Binding Cassette Sub-Family A Member 8
Database Links	Reactome: R-HSA-382556
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane Predominantly Expressed On The Sinusoidal Plasma Membrane
Alternative Antibody Names	Anti-Abc-Type Organic Anion Transporter Abca8 antibody Anti-Atp-Binding Cassette Sub-Family A Member 8 antibody Anti-ABCA8 antibody Anti-KIAA0822 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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