Aph 1b Blocking Peptide peptide (STJ503656) STJ503656-250 上海玉博生物科技有限公司

Aph 1b Blocking Peptide peptide (STJ503656)

简单介绍

Aph 1b Blocking Peptide peptide (STJ503656)

产品描述

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Aph 1b Blocking Peptide is synthetically produced from the 235-257 sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	APH1B
Gene ID:	83464
Uniprot ID:	APH1B_HUMAN
Immunogen Region:	235-257
Immunogen:	Synthetic peptide taken within amino acid region 235-257 of Human Presenilin stabilizing protein.

Tissue Specificity	Weakly or not expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen thymus, colon, skeletal muscle, heart and brain.
Function	Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (amyloid-beta precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.
Peptide Name	Gamma-Secretase Subunit Aph-1b Aph-1b Aph-1beta Presenilin-Stabilization Factor-Like
Database Links	Reactome: R-HSA-1251985 Reactome: R-HSA-193692 Reactome: R-HSA-205043 Reactome: R-HSA-2122948 Reactome: R-HSA-2644606 Reactome: R-HSA-2894862 Reactome: R-HSA-2979096 Reactome: R-HSA-3928665 Reactome: R-HSA-9013507 Reactome: R-HSA-9013700 Reactome: R-HSA-9017802 Reactome: R-HSA-977225
Cellular Localisation	Membrane Multi-Pass Membrane Protein
Alternative Peptide Names	Gamma-Secretase Subunit Aph-1b protein Aph-1b protein Aph-1beta protein Presenilin-Stabilization Factor-Like protein APH1B protein PSFL protein UNQ688 protein PRO1328 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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