Anti-ABCC1 antibody (850-1531) (STJ22459) STJ22459 上海玉博生物科技有限公司

Anti-ABCC1 antibody (850-1531) (STJ22459)

如果您对该产品感兴趣的话，可以
产品名称：Anti-ABCC1 antibody (850-1531) (STJ22459)
产品型号：STJ22459
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-ABCC1 antibody (850-1531) (STJ22459)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-MRP1/ABCC1 (850-1531) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:100-1:500 IHC-P 1:50-1:200 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ABCC1
Gene ID:	4363
Uniprot ID:	MRP1_HUMAN
Immunogen Region:	850-1531
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 850-1531 of human MRP1/ABCC1 (NP_004987.2).
Immunogen Sequence:	GSYQELLARDGAFAEFLRTY ASTEQEQDAEENGVTGVSGP GKEAKQMENGMLVTDSAGKQ LQRQLSSSSSYSGDISRHHN STAELQKAEAKKEETWKLME ADKAQTGQVKL

Tissue Specificity	Lung, testis and peripheral blood mononuclear cells.
Function	Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation. Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells. Mediates ATP-dependent, GSH-independent cyclic GMP-AMP (cGAMP) export. Thus, by limiting intracellular cGAMP concentrations negatively regulates the cGAS-STING pathway.
Protein Name	Multidrug Resistance-Associated Protein 1 Atp-Binding Cassette Sub-Family C Member 1 Glutathione-S-Conjugate-Translocating Atpase Abcc1 Leukotriene C(4 Transporter Ltc4 Transporter
Database Links	Reactome: R-HSA-189483 Reactome: R-HSA-2142691 Reactome: R-HSA-382556 Reactome: R-HSA-9707564 Reactome: R-HSA-9753281 Reactome: R-HSA-9758890
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Multidrug Resistance-Associated Protein 1 antibody Anti-Atp-Binding Cassette Sub-Family C Member 1 antibody Anti-Glutathione-S-Conjugate-Translocating Atpase Abcc1 antibody Anti-Leukotriene C(4 Transporter antibody Anti-Ltc4 Transporter antibody Anti-ABCC1 antibody Anti-MRP antibody Anti-MRP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Anti-ABCC1 antibody (850-1531) (STJ22459)