Anti-ABCC1 antibody (Internal) (STJ71643) STJ71643-100 上海玉博生物科技有限公司

Anti-ABCC1 antibody (Internal) (STJ71643)

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产品名称：Anti-ABCC1 antibody (Internal) (STJ71643)
产品型号：STJ71643-100
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-ABCC1 antibody (Internal) (STJ71643)

产品描述

Host:	Goat
Applications:	Pep-ELISA/WB
Reactivity:	Human/Mouse/Rat/Dog/Pig/Cow
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-ABCC1 (Internal) is suitable for use in ELISA and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-Recommended concentration:0.05-0.2µg/ml ELISA-antibody detection limit dilution 1:128000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	ABCC1
Gene ID:	4363
Uniprot ID:	MRP1_HUMAN
Immunogen Region:	Internal
Accession Number:	NP_004987.2; NP_063915.2; NP_063953.2; NP_063954.2; NP_063955.2
Specificity:	This antibody is expected to recognize all reported isoforms (NP_004987.2; NP_063915.2; NP_063953.2; NP_063954.2; NP_063955.2).
Immunogen Sequence:	HQSDLKVDENQKAYY

Function	Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation. Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells. Mediates ATP-dependent, GSH-independent cyclic GMP-AMP (cGAMP) export. Thus, by limiting intracellular cGAMP concentrations negatively regulates the cGAS-STING pathway.
Protein Name	Multidrug Resistance-Associated Protein 1 Atp-Binding Cassette Sub-Family C Member 1 Glutathione-S-Conjugate-Translocating Atpase Abcc1 Leukotriene C(4 Transporter Ltc4 Transporter
Database Links	Reactome: R-HSA-189483 Reactome: R-HSA-2142691 Reactome: R-HSA-382556 Reactome: R-HSA-9707564 Reactome: R-HSA-9753281 Reactome: R-HSA-9758890
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Multidrug Resistance-Associated Protein 1 antibody Anti-Atp-Binding Cassette Sub-Family C Member 1 antibody Anti-Glutathione-S-Conjugate-Translocating Atpase Abcc1 antibody Anti-Leukotriene C(4 Transporter antibody Anti-Ltc4 Transporter antibody Anti-ABCC1 antibody Anti-MRP antibody Anti-MRP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-ABCC1 antibody (Internal) (STJ71643)