Anti-ABCC10 antibody (1400-1492) (STJ11100471) STJ11100471 上海玉博生物科技有限公司

Anti-ABCC10 antibody (1400-1492) (STJ11100471)

简单介绍

Anti-ABCC10 antibody (1400-1492) (STJ11100471)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ABCC10 (1400-1492) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ABCC10
Gene ID:	89845
Uniprot ID:	MRP7_HUMAN
Immunogen Region:	1400-1492
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 1400-1492 of human ABCC10 (NP_001185863.1).
Immunogen Sequence:	AKILCIDEATASVDQKTDQL LQQTICKRFANKTVLTIAHR LNTILNSDRVLVLQAGRVVE LDSPATLRNQPHSLFQQLLQ SSQQGVPASLGGP

Tissue Specificity	In testis, localized to peritubular myoid cells, Leydig cells, along the basal membrane of Sertoli cells, moderately in the adluminal compartment of the seminiferous tubules, and in vascular endothelial cells. Isoform 1: Specifically expressed in spleen. Isoform 2: Widely expressed.
Function	ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4). May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier (Probable). Mediates multidrug resistance (MDR) in cancer cells by preventing the intracellular accumulation of certain antitumor drugs, such as, docetaxel and paclitaxel. Does not transport glycocholic acid, taurocholic acid, MTX, folic acid, cAMP, or cGMP.
Protein Name	Atp-Binding Cassette Sub-Family C Member 10 Multidrug Resistance-Associated Protein 7
Database Links	Reactome: R-HSA-382556
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane Basal Cell Membrane Localized To The Basal Membrane Of Sertoli Cells
Alternative Antibody Names	Anti-Atp-Binding Cassette Sub-Family C Member 10 antibody Anti-Multidrug Resistance-Associated Protein 7 antibody Anti-ABCC10 antibody Anti-MRP7 antibody Anti-SIMRP7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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