Anti-ABCC11 antibody (50-130 aa) (STJ190587) STJ190587 上海玉博生物科技有限公司

Anti-ABCC11 antibody (50-130 aa) (STJ190587)

简单介绍

Anti-ABCC11 antibody (50-130 aa) (STJ190587)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ATP-binding cassette sub-family C member 11 (50-130 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ABCC11
Gene ID:	85320
Uniprot ID:	MRP8_HUMAN
Immunogen Region:	50-130 aa
Specificity:	ABCCB Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 50-130

Function	ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Stimulates the ATP-dependent uptake of a range of physiological lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. Enhances also the cellular extrusion of cAMP and cGMP. Confers resistance to anticancer drugs, such as 5-fluorouracil (5-FU) and methotrexate. Probably functions to secrete earwax. Required for the secretion of components contributing to axillary odor formation.
Protein Name	Atp-Binding Cassette Sub-Family C Member 11 Multidrug Resistance-Associated Protein 8
Database Links	Reactome: R-HSA-382556
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Vacuole Membrane Cytoplasmic Vesicle Membrane Apical Cell Membrane
Alternative Antibody Names	Anti-Atp-Binding Cassette Sub-Family C Member 11 antibody Anti-Multidrug Resistance-Associated Protein 8 antibody Anti-ABCC11 antibody Anti-MRP8 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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