Human CD226 (DNAM-1) protein (Recombinant) (STJP000612) STJP000612 上海玉博生物科技有限公司

Human CD226 (DNAM-1) protein (Recombinant) (STJP000612)

简单介绍

Human CD226 (DNAM-1) protein (Recombinant) (STJP000612)

产品描述

Host:	HEK293
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human CD226 (DNAM-1)-protein was developed from hek293. For use in research applications.

Conjugation:	Unconjugated
Formulation:	Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Storage Instruction:	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity:	Recombinant Human CD226 activity was measured using Immobilized Human CD226 at 2 Mu g/ml ability to bind biotinylated Human CD112 with a linear ranger of 0.06-0.8 Mu g/ml NA

Gene Symbol:	CD226
Gene ID:	10666
Uniprot ID:	CD226_HUMAN
Immunogen Region:	ECD
Immunogen:	Optimized DNA sequence encoding extracellular domain of HumanCD226 (DNAM-1) including a C-terminal His tag was expressed in HEK293 cells. NA

Tissue Specificity	Expressed by peripheral blood T-lymphocytes.
Function	Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding.
Protein Name	Cd226 Antigen Dnax Accessory Molecule 1 Dnam-1 Cd Antigen Cd226
Database Links	Reactome: R-HSA-198933
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Cd226 Antigen protein Dnax Accessory Molecule 1 protein Dnam-1 protein Cd Antigen Cd226 protein CD226 protein DNAM1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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