Human CD24 protein (Recombinant) (C-mFc) {Biotin} (STJP001668) STJP001668 上海玉博生物科技有限公司

Human CD24 protein (Recombinant) (C-mFc) {Biotin} (STJP001668)

简单介绍

Human CD24 protein (Recombinant) (C-mFc) {Biotin} (STJP001668)

产品描述

Host:	HEK293
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human CD24-C-mFc protein was developed from hek293 and has a target region of C-mFc. For use in research applications.

Conjugation:	Biotin
Formulation:	Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range:	Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction:	The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).

Gene Symbol:	CD24
Gene ID:	100133941
Uniprot ID:	CD24_HUMAN
Immunogen Region:	Ser27-Gly59
Immunogen:	DNA sequence encoding Human CD24 (Primary Amine Labeling) including a C-mFc tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.

Post Translational Modifications	Extensively O-glycosylated.
Function	May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Protein Name	Signal Transducer Cd24 Small Cell Lung Carcinoma Cluster 4 Antigen Cd Antigen Cd24
Database Links	Reactome: R-HSA-373760
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor
Alternative Protein Names	Signal Transducer Cd24 protein Small Cell Lung Carcinoma Cluster 4 Antigen protein Cd Antigen Cd24 protein CD24 protein CD24A protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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