CD47 Positive Control for STJ500475 peptide (STJ507783) STJ507783-5 上海玉博生物科技有限公司

CD47 Positive Control for STJ500475 peptide (STJ507783)

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产品名称：CD47 Positive Control for STJ500475 peptide (STJ507783)
产品型号：STJ507783-5
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

CD47 Positive Control for STJ500475 peptide (STJ507783)

产品描述

Applications:	WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	CD47 Positive Control for STJ500475 is synthetically produced from the 1-200 sequence and is suitable for use in western blot applications.

Formulation:	Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	CD47
Gene ID:	961
Uniprot ID:	CD47_HUMAN
Immunogen Region:	1-200
Specificity:	This is positive control is recommended for use in combination with CD47 antibody STJ500475.
Immunogen:	Synthetic peptide corresponding to amino acids within region 1-200 on human CD47 protein.

Function	Adhesive protein that mediates cell-to-cell interactions. Acts as receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins. Involved in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, and immunoregulation. Plays a role in modulating pulmonary endothelin EDN1 signaling. Modulates nitrous oxide (NO) signaling, in response to THBS1, hence playing a role as a pressor agent, supporting blood pressure. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. Positively modulates FAS-dependent apoptosis in T-cells, perhaps by enhancing FAS clustering. Plays a role in suppressing angiogenesis and may be involved in metabolic dysregulation during normal aging. In response to THBS1, negatively modulates wound healing. Inhibits stem cell self-renewal, in response to THBS1, probably by regulation of the stem cell transcription factors POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells.
Peptide Name	Leukocyte Surface Antigen Cd47 Antigenic Surface Determinant Protein Oa3 Integrin-Associated Protein Iap Protein Mer6 Cd Antigen Cd47
Database Links	Reactome: R-HSA-202733 Reactome: R-HSA-216083 Reactome: R-HSA-391160 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Peptide Names	Leukocyte Surface Antigen Cd47 protein Antigenic Surface Determinant Protein Oa3 protein Integrin-Associated Protein protein Iap protein Protein Mer6 protein Cd Antigen Cd47 protein CD47 protein MER6 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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CD47 Positive Control for STJ500475 peptide (STJ507783)