Anti-ACHE antibody (C-Term) (STJ70663) STJ70663-100 上海玉博生物科技有限公司

Anti-ACHE antibody (C-Term) (STJ70663)

简单介绍

Anti-ACHE antibody (C-Term) (STJ70663)

产品描述

Host:	Goat
Applications:	Pep-ELISA/WB/IF/FC
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-ACHE (C-Term) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-0.3-1µg/ml IF-Strong expression of the protein seen in the cytoplasm and nucleus of U2OS cells. 10µg/ml ELISA-antibody detection limit dilution 1:64000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	ACHE
Gene ID:	43
Uniprot ID:	ACES_HUMAN
Immunogen Region:	C-Term
Accession Number:	NP_000656.1; NP_001269378.1
Specificity:	This antibody is expected to recognise isoform NP_000656.1 only (the ubiquitously expressed, hydrophillic form).
Immunogen Sequence:	QFDHYSKQDRCSDL

Function	Hydrolyzes rapidly the acetylcholine neurotransmitter released into the synaptic cleft allowing to terminate the signal transduction at the neuromuscular junction. Role in neuronal apoptosis.
Protein Name	Acetylcholinesterase Ache
Database Links	Reactome: R-HSA-112311 Reactome: R-HSA-1483191 Reactome: R-HSA-422085
Cellular Localisation	Synapse Secreted Cell Membrane Peripheral Membrane Protein Isoform T: Nucleus Only Observed In Apoptotic Nuclei Isoform H: Cell Membrane Lipid-Anchor Gpi-Anchor Extracellular Side
Alternative Antibody Names	Anti-Acetylcholinesterase antibody Anti-Ache antibody Anti-ACHE antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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