Human CD32a (FcgRIIa) protein (Recombinant) {Biotin} (STJP000197) STJP000197 上海玉博生物科技有限公司

Human CD32a (FcgRIIa) protein (Recombinant) {Biotin} (STJP000197)

简单介绍

Human CD32a (FcgRIIa) protein (Recombinant) {Biotin} (STJP000197)

产品描述

Host:	HEK293
Applications:	ELISA/WB
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human CD32a (FcgRIIa)-protein was developed from hek293. For use in research applications.

Conjugation:	Biotin
Formulation:	Lyophilised 0.2 Mu m filtered PBS solution, pH7.2.
Dilution Range:	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL.
Storage Instruction:	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA

Gene Symbol:	FCGR2A
Gene ID:	2212
Uniprot ID:	FCG2A_HUMAN
Immunogen Region:	ECD
Immunogen:	Optimized DNA sequence encoding Human extracellular domain of human CD32aincluding a C-terminal 6His tag was expressed in HEK293 cells. CD32a was further labled by Biotin for detection by avidin conjugated secondary probes. NA

Tissue Specificity	Found on monocytes, neutrophils and eosinophil platelets.
Post Translational Modifications	Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
Function	Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Protein Name	Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A Igg Fc Receptor Ii-A Cdw32 Fc-Gamma Rii-A Fc-Gamma-Riia Fcrii-A Cd Antigen Cd32
Database Links	Reactome: R-HSA-2029481 Reactome: R-HSA-2029482 Reactome: R-HSA-2029485 Reactome: R-HSA-6798695 Reactome: R-HSA-9664323
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A protein Igg Fc Receptor Ii-A protein Cdw32 protein Fc-Gamma Rii-A protein Fc-Gamma-Riia protein Fcrii-A protein Cd Antigen Cd32 protein FCGR2A protein CD32 protein FCG2 protein FCGR2A1 protein IGFR2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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