Human CD38 protein (Recombinant) (STJP000502) STJP000502 上海玉博生物科技有限公司

Human CD38 protein (Recombinant) (STJP000502)

简单介绍

Human CD38 protein (Recombinant) (STJP000502)

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Host:	HEK293
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human CD38-protein was developed from hek293. For use in research applications.

Conjugation:	Unconjugated
Formulation:	0.2 Mu m filtered PBS solution, pH7.2.
Storage Instruction:	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA

Gene Symbol:	CD38
Gene ID:	952
Uniprot ID:	CD38_HUMAN
Immunogen Region:	ECD
Immunogen:	Optimized DNA sequence encoding Human extracellular domain of human CD38 including a C-terminal 6His tag was expressed in HEK293 cells. NA

Tissue Specificity	Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
Function	Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity.
Protein Name	Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 2'-Phospho-Adp-Ribosyl Cyclase 2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase 2'-Phospho-Cyclic-Adp-Ribose Transferase Adp-Ribosyl Cyclase 1 Adprc 1 Cyclic Adp-Ribose Hydrolase 1 Cadpr Hydrolase 1 T10 Cd Antigen Cd38
Database Links	Reactome: R-HSA-196807
Cellular Localisation	Cell Surface Membrane Single-Pass Type Ii Membrane Protein
Alternative Protein Names	Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 protein 2'-Phospho-Adp-Ribosyl Cyclase protein 2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase protein 2'-Phospho-Cyclic-Adp-Ribose Transferase protein Adp-Ribosyl Cyclase 1 protein Adprc 1 protein Cyclic Adp-Ribose Hydrolase 1 protein Cadpr Hydrolase 1 protein T10 protein Cd Antigen Cd38 protein CD38 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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