Human CD40 (TNFRSF5) protein (Recombinant) (STJP000492) STJP000492 上海玉博生物科技有限公司

Human CD40 (TNFRSF5) protein (Recombinant) (STJP000492)

简单介绍

Human CD40 (TNFRSF5) protein (Recombinant) (STJP000492)

产品描述

Host:	HEK293
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human CD40 (TNFRSF5)-protein was developed from hek293. For use in research applications.

Conjugation:	Unconjugated
Formulation:	Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Storage Instruction:	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity:	The activity was tested by the ability of immobilized recombinant human CD40 to bind Human CD40 Ligand with a linear range of 10-500 ng/ml NA

Gene Symbol:	CD40
Gene ID:	958
Uniprot ID:	TNR5_HUMAN
Immunogen Region:	ECD
Immunogen:	Optimized DNA sequence encoding extracellular domain of Human CD40 including a C-terminal His tag was expressed in HEK293 cells. NA

Tissue Specificity	B-cells and in primary carcinomas.
Function	Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Protein Name	Tumor Necrosis Factor Receptor Superfamily Member 5 B-Cell Surface Antigen Cd40 Bp50 Cd40l Receptor Cdw40 Cd Antigen Cd40
Database Links	Reactome: R-HSA-198933 P25942-1 Reactome: R-HSA-5668541 P25942-1 Reactome: R-HSA-5676594 P25942-1
Cellular Localisation	Isoform I: Cell Membrane Single-Pass Type I Membrane Protein Isoform Ii: Secreted
Alternative Protein Names	Tumor Necrosis Factor Receptor Superfamily Member 5 protein B-Cell Surface Antigen Cd40 protein Bp50 protein Cd40l Receptor protein Cdw40 protein Cd Antigen Cd40 protein CD40 protein TNFRSF5 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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