Human Serpin D1/Heparin cofactor 2 protein (Recombinant) (C-His) (STJP001220) STJP001220-20 上海玉博生物科技有限公司

Human Serpin D1/Heparin cofactor 2 protein (Recombinant) (C-His) (STJP001220)

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产品名称：Human Serpin D1/Heparin cofactor 2 protein (Recombinant) (C-His) (STJP001220)
产品型号：STJP001220-20
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human Serpin D1/Heparin cofactor 2 protein (Recombinant) (C-His) (STJP001220)

产品描述

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Serpin D1/Heparin cofactor 2-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of 50mM TRIS, 150mM NaCl, pH7.5. Contact us for customized product form or formulation.
Immunoreactivity:	Measured by its ability to inhibit Recombinant Human Coagulation Factor II/Thrombin cleavage of a fluorogenic peptide substrate Boc-VPR-AMC. The IC50 value is

Gene Symbol:	SERPIND1
Gene ID:	3053
Uniprot ID:	HEP2_HUMAN
Immunogen:	Recombinant Human Serpin D1/Heparin cofactor 2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly20-Ser499) of human Serpin D1/Heparin Cofactor II (Accession #NP_000176.2.) fused with a 6×His tag

Post Translational Modifications	Phosphorylated by FAM20C in the extracellular medium.
Function	Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
Protein Name	Heparin Cofactor 2 Heparin Cofactor Ii Hc-Ii Protease Inhibitor Leuserpin-2 Hls2 Serpin D1
Database Links	Reactome: R-HSA-140837 Reactome: R-HSA-140875 Reactome: R-HSA-381426 Reactome: R-HSA-8957275
Alternative Protein Names	Heparin Cofactor 2 protein Heparin Cofactor Ii protein Hc-Ii protein Protease Inhibitor Leuserpin-2 protein Hls2 protein Serpin D1 protein SERPIND1 protein HCF2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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