Orexin A Positive Control for STJ502011 peptide (STJ504498) STJ504498-5 上海玉博生物科技有限公司

Orexin A Positive Control for STJ502011 peptide (STJ504498)

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产品名称：Orexin A Positive Control for STJ502011 peptide (STJ504498)
产品型号：STJ504498-5
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Orexin A Positive Control for STJ502011 peptide (STJ504498)

产品描述

Applications:	WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Orexin A Positive Control for STJ502011 is synthetically produced from the sequence and is suitable for use in western blot applications.

Formulation:	Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range:	WB: 1:500
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Hcrt
Gene ID:	15171
Uniprot ID:	OREX_MOUSE
Specificity:	This is positive control is recommended for use in combination with Orexin A antibody STJ502011.

Tissue Specificity	Restricted to neuronal cell bodies of the dorsal and lateral hypothalamus.
Post Translational Modifications	Specific enzymatic cleavages at paired basic residues yield the different active peptides.
Function	Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A: Binds to orexin receptors HCRTR1/OX1R and HCRTR2/OX2R with a high affinity. Stimulates food intake. Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner. Orexin-B: Binds to orexin receptor HCRTR2/OX2R only. Stimulates food intake. Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner.
Peptide Name	Hypocretin Neuropeptide Precursor Hypocretin Hcrt Orexin Precursor Prepro-Orexin Preprohypocretin Cleaved Into - Orexin-A Hypocretin-1 Hcrt1 - Orexin-B Hypocretin-2 Hcrt2
Database Links	Reactome: R-MMU-389397 Reactome: -MMU-416476
Cellular Localisation	Rough Endoplasmic Reticulum Cytoplasmic Vesicle Synapse Associated With Perikaryal Rough Endoplasmic Reticulum As Well As Cytoplasmic Large Granular Vesicles At Synapses
Alternative Peptide Names	Hypocretin Neuropeptide Precursor protein Hypocretin protein Hcrt protein Orexin Precursor protein Prepro-Orexin protein Preprohypocretin Cleaved Into - Orexin-A protein Hypocretin-1 protein Hcrt1 - Orexin-B protein Hypocretin-2 protein Hcrt2 protein Hcrt protein Ox protein Ppox protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Orexin A Positive Control for STJ502011 peptide (STJ504498)