SGK2 Blocking Peptide for STJ502982 peptide (STJ504917) STJ504917-250 上海玉博生物科技有限公司

SGK2 Blocking Peptide for STJ502982 peptide (STJ504917)

简单介绍

SGK2 Blocking Peptide for STJ502982 peptide (STJ504917)

产品描述

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	SGK2 Blocking Peptide for STJ502982 is synthetically produced from the 377-427 sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	SGK2
Gene ID:	10110
Uniprot ID:	SGK2_HUMAN
Immunogen Region:	377-427
Specificity:	This blocking peptide is recommended for use in combination with SGK2 antibody, STJ502982
Immunogen:	Synthetic peptide taken within amino acid region 377-427 on human Sgk2 protein.

Tissue Specificity	Highly expressed in liver, kidney and pancreas, and at lower levels in brain.
Post Translational Modifications	Activated by phosphorylation on Ser-356 by an unknown kinase (may be mTORC2 but not confirmed), transforming it into a substrate for PDPK1 which then phosphorylates it on Thr-193.
Function	Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.
Peptide Name	Serine/Threonine-Protein Kinase Sgk2 Serum/Glucocorticoid-Regulated Kinase 2
Database Links	Reactome: R-HSA-2672351
Cellular Localisation	Cytoplasm Nucleus
Alternative Peptide Names	Serine/Threonine-Protein Kinase Sgk2 protein Serum/Glucocorticoid-Regulated Kinase 2 protein SGK2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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