Anti-ARPC2 antibody (1-300) (STJ112687) STJ112687 上海玉博生物科技有限公司

Anti-ARPC2 antibody (1-300) (STJ112687)

简单介绍

Anti-ARPC2 antibody (1-300) (STJ112687)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ARPC2 (1-300) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ARPC2
Gene ID:	10109
Uniprot ID:	ARPC2_HUMAN
Immunogen Region:	1-300
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ARPC2 (NP_690601.1).
Immunogen Sequence:	MILLEVNNRIIEETLALKFE NAAAGNKPEAVEVTFADFDG VLYHISNPNGDKTKVMVSIS LKFYKELQAHGADELLKRVY GSFLVNPESGYNVSLLYDLE NLPASKDSIVHQAGMLKRNC FASVFEKYFQFQEEGKEGEN RAVIHYRDDETMYVESKKDR VTVVFSTVFKDDDDVVIGKV FMQEFKEGRRASHTAPQVLF SHREPPLELKDTDAAVGDNI GYITFVLFPRHTNASARDN

Function	Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
Protein Name	Actin-Related Protein 2/3 Complex Subunit 2 Arp2/3 Complex 34 Kda Subunit P34-Arc
Database Links	Reactome: R-HSA-2029482 Reactome: R-HSA-3928662 Reactome: R-HSA-5663213 Reactome: R-HSA-8856828 Reactome: R-HSA-9664422
Cellular Localisation	Cytoplasm Cytoskeleton Cell Projection Synapse Synaptosome Nucleus
Alternative Antibody Names	Anti-Actin-Related Protein 2/3 Complex Subunit 2 antibody Anti-Arp2/3 Complex 34 Kda Subunit antibody Anti-P34-Arc antibody Anti-ARPC2 antibody Anti-ARC34 antibody Anti-PRO2446 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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