Anti-ARPC5 antibody (58-108 aa) (STJ194358) STJ194358 上海玉博生物科技有限公司

Anti-ARPC5 antibody (58-108 aa) (STJ194358)

简单介绍

Anti-ARPC5 antibody (58-108 aa) (STJ194358)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Actin-related protein 2/3 complex subunit 5 (58-108 aa) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ARPC5
Gene ID:	10092
Uniprot ID:	ARPC5_HUMAN
Immunogen Region:	58-108 aa
Specificity:	This antibody detects endogenous levels of ARPC5 at Human/Mouse/Rat
Immunogen:	Synthesized peptide derived from the human ARPC5 at the amino acid range 58-108

Function	Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
Protein Name	Actin-Related Protein 2/3 Complex Subunit 5 Arp2/3 Complex 16 Kda Subunit P16-Arc
Database Links	Reactome: R-HSA-2029482 Reactome: R-HSA-3928662 Reactome: R-HSA-5663213 Reactome: R-HSA-6798695 Reactome: R-HSA-8856828 Reactome: R-HSA-9664422
Cellular Localisation	Cytoplasm Cytoskeleton Cell Projection Nucleus
Alternative Antibody Names	Anti-Actin-Related Protein 2/3 Complex Subunit 5 antibody Anti-Arp2/3 Complex 16 Kda Subunit antibody Anti-P16-Arc antibody Anti-ARPC5 antibody Anti-ARC16 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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