Human CLSTN2 (Calsyntenin 2) Sandwich ELISA Kit (STJE0007995) STJE0007995 上海玉博生物科技有限公司

Human CLSTN2 (Calsyntenin 2) Sandwich ELISA Kit (STJE0007995)

简单介绍

Human CLSTN2 (Calsyntenin 2) Sandwich ELISA Kit (STJE0007995)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.059ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This CLSTN2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	CLSTN2
Gene ID:	64084
Uniprot ID:	CSTN2_HUMAN
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Restricted to the brain.
Post Translational Modifications	Proteolytically processed under normal cellular conditions. A primary zeta-cleavage generates a large extracellular (soluble) N-terminal domain (sAlc) and a short C-terminal transmembrane fragment (CTF1). A secondary cleavage catalyzed by gamma-secretase within the transmembrane domain releases the beta-Alc-gamma chain in the extracellular milieu and produces an intracellular fragment (AlcICD). This processing is strongly suppressed in the tripartite complex formed with APBA2 and APP, which seems to prevent the association with PSEN1.
Function	Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate synapse formation, and which is involved in learning and memory. Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with neurexin-alpha at the presynaptic membrane.
Protein Name	Calsyntenin-2 Alcadein-Gamma Alc-Gamma
Database Links
Cellular Localisation	Postsynaptic Cell Membrane Single-Pass Type I Membrane Protein Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Cell Projection Dendrite Most Prominent In The Postsynaptic Specializations Of Asymmetric (Type I) Synapses With Both Axodendritic And Axospinous Localization
Alternative ELISA Names	Calsyntenin-2 ELISA kit Alcadein-Gamma ELISA kit Alc-Gamma ELISA kit CLSTN2 ELISA kit CS2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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