Mouse IL-36Ra/IL-1F5 protein (Recombinant) (NO-tag) (STJP001975) STJP001975 上海玉博生物科技有限公司

Mouse IL-36Ra/IL-1F5 protein (Recombinant) (NO-tag) (STJP001975)

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产品名称：Mouse IL-36Ra/IL-1F5 protein (Recombinant) (NO-tag) (STJP001975)
产品型号：STJP001975
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Mouse IL-36Ra/IL-1F5 protein (Recombinant) (NO-tag) (STJP001975)

产品描述

Host:	HEK293 cells
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Mouse IL-36Ra/IL-1F5-NO-tag protein was developed from hek293 cells and has a target region of NO-tag. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Endotoxin:	＜1EU/Mu g

Gene Symbol:	IL36RN
Gene ID:	54450
Uniprot ID:	I36RA_MOUSE
Immunogen Region:	Val3-Asp156
Immunogen:	Recombinant Mouse IL-36Ra/IL-1F5 Protein is produced by expression system. The target protein is expressed with sequence (Val3-Asp156) of mouse IL-36Ra/IL-1F5 (Accession #NP_062324.2) fused with no additional amino acid.

Post Translational Modifications	Removal of N-terminal methionine is necessary for full antagonistic activity.
Function	Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2/IL-36R and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response.similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.
Protein Name	Interleukin-36 Receptor Antagonist Protein Il-36ra Interleukin-1 Hy1 Il-1hy1 Interleukin-1 Delta Il-1 Delta Interleukin-1 Family Member 5 Il-1f5 Interleukin-1 Homolog 3 Il-1h3 Interleukin-1-Like Protein 1 Il-1l1
Database Links	Reactome: R-MMU-9014826
Cellular Localisation	Cytoplasm Secreted The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10 It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion
Alternative Protein Names	Interleukin-36 Receptor Antagonist Protein protein Il-36ra protein Interleukin-1 Hy1 protein Il-1hy1 protein Interleukin-1 Delta protein Il-1 Delta protein Interleukin-1 Family Member 5 protein Il-1f5 protein Interleukin-1 Homolog 3 protein Il-1h3 protein Interleukin-1-Like Protein 1 protein Il-1l1 protein IL36RN protein Fil1d protein Il1f5 protein Il1h3 protein Il1hy1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Mouse IL-36Ra/IL-1F5 protein (Recombinant) (NO-tag) (STJP001975)