Mouse IL-7 protein (Recombinant) (C-6His) (STJP001939) STJP001939 上海玉博生物科技有限公司

Mouse IL-7 protein (Recombinant) (C-6His) (STJP001939)

简单介绍

Mouse IL-7 protein (Recombinant) (C-6His) (STJP001939)

产品描述

Host:	HEK293 cells
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Mouse IL-7-C-6His protein was developed from hek293 cells and has a target region of C-6His. For use in research applications.

Formulation:	Supplied as a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity:	Measured in a cell proliferation assay using murine 2E8 cells. The ED50 for this effect is 0.8-3.2 ng/mL, corresponding to a specific activity of 3.23×105~1.25×106 units/mg.

Gene Symbol:	Il7
Gene ID:	16196
Uniprot ID:	IL7_MOUSE
Immunogen Region:	Glu26-Ile154
Immunogen:	Recombinant Mouse IL-7 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu26-Ile154) of mouse IL7 (Accession #NP_032397.1) fused with and a 6×His tag at the C-terminus.

Function	Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis. Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG. Binding to the receptor leads to activation of various kinases including JAK1 or JAK3 depending on the cell type and subsequently propagation of signals through activation of several downstream signaling pathways including the PI3K/Akt/mTOR or the JAK-STAT5.
Protein Name	Interleukin-7 Il-7
Cellular Localisation	Secreted
Alternative Protein Names	Interleukin-7 protein Il-7 protein Il7 protein Il-7 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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