SGLT1 Blocking Peptide peptide (STJ504920) STJ504920-250 上海玉博生物科技有限公司

SGLT1 Blocking Peptide peptide (STJ504920)

如果您对该产品感兴趣的话，可以
产品名称：SGLT1 Blocking Peptide peptide (STJ504920)
产品型号：STJ504920-250
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

SGLT1 Blocking Peptide peptide (STJ504920)

产品描述

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	SGLT1 Blocking Peptide is synthetically produced from the 603-623 sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	SLC5A1
Gene ID:	6523
Uniprot ID:	SC5A1_HUMAN
Immunogen Region:	603-623
Immunogen:	Synthetic peptide corresponding to amino acids 603-623 of Human SGLT1.

Tissue Specificity	Expressed in intestine. Expressed in endometrial cells.
Post Translational Modifications	N-glycosylation is not necessary for the cotransporter function.
Function	Electrogenic Na(+)-coupled sugar simporter that actively transports D-glucose or D-galactose at the plasma membrane, with a Na(+) to sugar coupling ratio of 2:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump. Has a primary role in the transport of dietary monosaccharides from enterocytes to blood. Responsible for the absorption of D-glucose or D-galactose across the apical brush-border membrane of enterocytes, whereas basolateral exit is provided by GLUT2. Additionally, functions as a D-glucose sensor in enteroendocrine cells, triggering the secretion of the incretins GCG and GIP that control food intake and energy homeostasis. Together with SGLT2, functions in reabsorption of D-glucose from glomerular filtrate, playing a nonredundant role in the S3 segment of the proximal tubules. Transports D-glucose into endometrial epithelial cells, controlling glycogen synthesis and nutritional support for the embryo as well as the decidual transformation of endometrium prior to conception. Acts as a water channel enabling passive water transport across the plasma membrane in response to the osmotic gradient created upon sugar and Na(+) uptake. Has high water conductivity, comparable to aquaporins, and therefore is expected to play an important role in transepithelial water permeability, especially in the small intestine.
Peptide Name	Sodium/Glucose Cotransporter 1 Na(+/Glucose Cotransporter 1 High Affinity Sodium-Glucose Cotransporter Solute Carrier Family 5 Member 1
Database Links	Reactome: R-HSA-189200 Reactome: R-HSA-5656364 Reactome: R-HSA-8981373
Cellular Localisation	Apical Cell Membrane Multi-Pass Membrane Protein
Alternative Peptide Names	Sodium/Glucose Cotransporter 1 protein Na(+/Glucose Cotransporter 1 protein High Affinity Sodium-Glucose Cotransporter protein Solute Carrier Family 5 Member 1 protein SLC5A1 protein NAGT protein SGLT1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

SGLT1 Blocking Peptide peptide (STJ504920)